Ginsenoside Rg1

Ginsenoside Rg1 is one of the major active components of Panax ginseng. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. Ginsenoside Rg1 also reduces NF-κB nuclear translocation.

Product Specifications

CAS Number

[22427-39-0]

Product Name Alternative

Panaxoside A; Panaxoside Rg1

UNSPSC

12352005

Hazard Statement

H302

Target

Amyloid-β; Apoptosis; NF-κB

Type

Natural Products

Related Pathways

Apoptosis; Neuronal Signaling; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Ginsenoside-Rg1.html

Concentration

10mM

Purity

99.91

Solubility

DMSO : ≥ 100 mg/mL|H2O : 10 mg/mL (ultrasonic)

Smiles

[H][C@]12C(C)(C)[C@@H](O)CC[C@]1(C)[C@]3([H])[C@@]([C@@](CC[C@]4([H])[C@@](CC/C=C(C)/C)(C)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)(C)[C@]4([H])[C@H](O)C3)(C)C[C@@H]2O[C@]6([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O

Molecular Formula

C42H72O14

Molecular Weight

801.01

Precautions

H302

References & Citations

[1]Li N, et al. A UPLC/MS-based metabolomics investigation of the protective effect of ginsenosides Rg1 and Rg2 in mice with Alzheimer's disease. J Ginseng Res. 2016 Jan;40 (1) :9-17.|[2]Zhang L, et al. Ginsenoside Rg1 attenuates adjuvant-induced arthritis in rats via modulation of PPAR-γ/NF-κB signal pathway. Oncotarget. 2017 Jul 24;8 (33) :55384-55393.|[3]Wang P, et al. Effect of ginsenoside Rg1 on proliferation and differentiation of human dental pulp cells in vitro. Aust Dent J. 2012 Jun;57 (2) :157-65.