Cathepsin K inhibitor 6
Cathepsin K inhibitor 6 (compound 19) is an inhibitor of cathepsin K (Cat K) with an IC50 of 17 nM. Cathepsin K inhibitor 6 also has inhibitory effects on other isoforms, with IC50s of 0.05 μM (Cat L) and 0.3 μM (Cat B), respectively[1].
Product Specifications
CAS Number
[325775-42-6]
UNSPSC
12352005
Target
Cathepsin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/naaa-in-2.html
Purity
98.18
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CN1CC(C1)CNS(=O)(C2=CC=CC=C2)=O
Molecular Formula
C11H13N3O2S
Molecular Weight
251.30
References & Citations
[1]Falgueyret JP, et al. Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L. J Med Chem. 2001 Jan 4;44 (1) :94-104.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cathepsin B; Cathepsin K; Cathepsin L
Available Sizes
Curated Selection
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