2-Methoxy-2,4-diphenylfuran-3-one

2-Methoxy-2,4-diphenylfuran-3-one is a fluorescent compound which can be used to label gelatin as a substrate for detection of the gelatin degrading MMP-2 and MMP-9 by zymography[1].

Product Specifications

CAS Number

[50632-57-0]

UNSPSC

12171500

Hazard Statement

H315-H319-H335

Target

MMP

Type

Dye Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/2-methoxy-2-4-diphenylfuran-3-one.html

Solubility

10 mM in DMSO

Smiles

COC1(C2=CC=CC=C2)C(=O)C(=CO1)C3=CC=CC=C3

Molecular Formula

C17H14O3

Molecular Weight

266.29

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

References & Citations

[1]Peter Jackson. Detection of phosphoproteins. WO2006070180.|[2]Danqing Min, et al. 2-Methoxy-2,4-diphenyl-3 (2H) -furanone-labeled gelatin zymography and reverse zymography: a rapid real-time method for quantification of matrix metalloproteinases-2 and -9 and tissue inhibitors of metalloproteinases. Electrophoresis. 20