DPPD-Q

DPPD-Q is an oxidized derivative of the antioxidant and substituted p-phenylenediamine DPPD, which is found in tire wear particles and crumb rubber, particulate matter 2.5 (PM2.5), and wastewater influent and effluent. DPPD-Q inhibits jack bean urease by 91.4% at 5 µM[1][2].

Product Specifications

CAS Number

[3421-08-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/dppd-q.html

Purity

98.0

Smiles

O=C1C=C(C(C=C1NC2=CC=CC=C2)=O)NC3=CC=CC=C3

Molecular Formula

C18H14N2O2

Molecular Weight

290.32

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang W, et al. Beyond Substituted p-Phenylenediamine Antioxidants: Prevalence of Their Quinone Derivatives in PM2.5. Environ Sci Technol. 2022 Aug 2;56 (15) :10629-10637. |[2]Cao G, et al. Occurrence and Fate of Substituted p-Phenylenediamine-Derived Quinones in Hong Kong Wastewater Treatment Plants. Environ Sci Technol. 2023 Oct 17;57 (41) :15635-15643.