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Ambroxol (hydrochloride) (Standard)

Ambroxol (hydrochloride) (Standard) is the analytical standard of Ambroxol (hydrochloride) . This product is intended for research and analytical applications. Ambroxol hydrochloride (NA-872 hydrochloride), an active metabolite of the proagent Bromhexine, has potent expectorant effects. Ambroxol hydrochloride is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol hydrochloride induces lung autophagy and has the potential for Parkinson disease and neuronopathic Gaucher disease research[1][2].

Product Specifications

CAS Number

23828-92-4

Product Name Alternative

NA-872 (hydrochloride) (Standard)

UNSPSC

12352005

Target

Autophagy; Glycosidase; Reference Standards

Type

Reference Standards

Related Pathways

Autophagy; Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ambroxol-hydrochloride-standard.html

Purity

99.91

Smiles

O[C@H]1CC[C@H](NCC2=CC(Br)=CC(Br)=C2N)CC1.[H]Cl

Molecular Formula

C13H19Br2ClN2O

Molecular Weight

414.56

References & Citations

[1]Vojo Deretic, et al. Enhancement of lung levels of antibiotics by ambroxol and bromhexine. Expert Opin Drug Metab Toxicol. 2019 Mar;15 (3) :213-218.|[2]Anna Migdalska-Richards, et al. Ambroxol effects in glucocerebrosidase and α-synuclein transgenic mice. Ann Neurol. 2016 Nov;80 (5) :766-775.

Shipping Conditions

Blue Ice

Storage Conditions

4°C, sealed and dry storage, away from light and moisture

Scientific Category

Reference Standards

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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