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Elab Fluor® 700 Anti-Human CD329 Antibody[K8]

Product Specifications

Background

Siglecs are cell surface receptors belonging to the immunoglobulin superfamily that recognize sugar antigens. The extracellular domain of siglec-9 contains an IgV region, which binds sialic acid, followed by two IgC regions. Siglec 9 and siglec 6-8,10-12 are CD33 (siglec 3) like siglecs, which have two ITIMs in the cytoplasmic tails, suggesting their functional involvement in signal transduction. It is highly expressed on neutrophils and monocytes, and at lower levels on the subpopulations of T and B lymphocytes and NK cells. Siglec-9 plays a role in negative regulation of T cell activation, and it also affects neutrophil apoptosis.

Abbreviation

CD329

Gene ID

27180

UniProt

Q9Y336

Host

Mouse

Reactivity

Human

Target

Siglec-9; Sialic acid-binding Ig-like lectin-9

Clonality

Monoclonal

Clone

K8

Conjugation

Elab Fluor®700

Applications

FCM

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Product Datasheet

https://789.bio/ea/alz1t9

Product MSDS

https://789.bio/eb/Ph1hPK

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1, κ

Available Sizes

Curated Selection

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