Veratryl alcohol

Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP) . Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy[1][2][3][4].

Product Specifications

CAS Number

[93-03-8]

Product Name Alternative

3,4-Dimethoxybenzyl alcohol

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; Endogenous Metabolite

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/3-4-dimethoxybenzenemethanol.html

Purity

99.98

Solubility

Ethanol : 100 mg/mL (ultrasonic)

Smiles

OCC1=CC=C(OC)C(OC)=C1

Molecular Formula

C9H12O3

Molecular Weight

168.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Leisola MS, et al. Enzymatic determination of veratryl alcohol. Anal Biochem. 1986 May 15;155 (1) :108-11.|[2]Arias ME, et al. Kraft pulp biobleaching and mediated oxidation of a nonphenolic substrate by laccase from Streptomyces cyaneus CECT 3335. Appl Environ Microbiol. 2003 Apr;69 (4) :1953-8.|[3]Koduri RS, et al., Oxidation of guaiacol by lignin peroxidase. Role of veratryl alcohol. J Biol Chem. 1995 Sep 22;270 (38) :22254-8. |[4]Fu S, et al., Veratryl Alcohol Attenuates the Virulence and Pathogenicity of Pseudomonas aeruginosa Mainly via Targeting las Quorum-Sensing System. Microorganisms. 2024 May 14;12 (5) :985.