HJ-PI01
Product Specifications
Product Name Alternative
10-Acetylphenoxazine
UNSPSC Description
HJ-PI01 (10-Acetylphenoxazine) is an orally active Pim-2 inhibitor. HJ-PI01 induces apoptosis and autophagic cell death of cancer cells. HJ-PI01 inhibits tumor growth in MDA-MB-231 xenograft mice. HJ-PI01 can be used for cancer research[1].
Target Antigen
Pim
Type
Reference compound
Related Pathways
JAK/STAT Signaling
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hj-pi01.html
Purity
99.72
Solubility
DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
CC(N1C2=C(C=CC=C2)OC3=CC=CC=C13)=O
Molecular Weight
225.24
References & Citations
[1]Zhao YQ, et al. Characterization of HJ-PI01 as a novel Pim-2 inhibitor that induces apoptosis and autophagic cell death in triple-negative human breast cancer. Acta Pharmacol Sin. 2016 Sep;37(9):1237-50.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-129163/HJ-PI01-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-129163/HJ-PI01-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
6192-43-4
Available Sizes
Curated Selection
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