SF5
SF5 (2,2-Diphenylethyl isothiocyanate) is a sulforaphane analog. SF5 inhibits apoptosis by the JNK-p53-caspase pathway. SF5 can be used as a new renal protective agent for drug-resistant acute renal disease[1].
Product Specifications
CAS Number
34634-22-5
Product Name Alternative
2,2-Diphenylethyl isothiocyanate
UNSPSC
12352005
Hazard Statement
H315, H317, H319, H330, H334, H335, H351, H412
Target
Apoptosis; Caspase; JNK; MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sf5.html
Purity
99.83
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
S=C=NCC(C1=CC=CC=C1)C2=CC=CC=C2
Molecular Formula
C15H13NS
Molecular Weight
239.34
Precautions
H315, H317, H319, H330, H334, H335, H351, H412
References & Citations
[1]Kim T, et al. The synthesis of sulforaphane analogues and their protection effect against cisplatin induced cytotoxicity in kidney cells. Bioorg Med Chem Lett. 2015 Jan 1;25 (1) :62-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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