Thonningianin B

Thonningianin B is an antioxidant and an autophagy enhancer[1][2].

Product Specifications

CAS Number

[271579-12-5]

UNSPSC

12352005

Target

Autophagy

Type

Natural Products

Related Pathways

Autophagy

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/thonningianin-b.html

Purity

99.94

Solubility

DMSO : 66.67 mg/mL (ultrasonic) |Methanol : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=C(O)C=C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](COC3=O)O2)OC(C4=CC(O)=C(O)C(O)=C4C5=C(O)C(O)=C(O)C=C53)=O)O)O)C=C1O)CCC6=CC=CC=C6

Molecular Formula

C35H30O17

Molecular Weight

722.60

References & Citations

[1]Ohtani II, et al. Thonningianins A and B, new antioxidants from the African medicinal herb Thonningia sanguinea. J Nat Prod. 2000 May;63 (5) :676-9.|[2]Zhou XG, et al. Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer's disease. Inflamm Regen. 2022 Aug 3;42 (1) :25.