L-Cystathionine (dihydrochloride)

L-Cystathionine (dihydrochloride) is a nonprotein thioether and is a key amino acid associated with the metabolic state of sulfur-containing amino acids. L-Cystathionine (dihydrochloride) protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs) . L-Cystathionine (dihydrochloride) plays an important role in cardiovascular protection[1][2].

Product Specifications

CAS Number

[61125-50-6]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Endogenous Metabolite

Type

Reference compound

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Neuroscience-Neurodegeneration

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/l-cystathionine-dihydrochloride.html

Purity

99.77

Solubility

H2O : 120 mg/mL (ultrasonic)

Smiles

N[C@@H](CCSC[C@H](N)C(O)=O)C(O)=O.Cl.Cl

Molecular Formula

C7H16Cl2N2O4S

Molecular Weight

295.18

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang X, et al. L-Cystathionine Protects against Homocysteine-Induced Mitochondria-Dependent Apoptosis of Vascular Endothelial Cells. Oxid Med Cell Longev. 2019;2019:1253289.|[2]Amino Y, et al. Synthesis and evaluation of L-cystathionine as a standard for amino acid analysis. Biosci Biotechnol Biochem. 2017;81 (1) :95-101.