GS-441524
GS-441524, predominant metabolite of Remdesivir and superior to Remdesivir against Covid-19 , shows comparable efficacy in cell-based models of primary human lung and cat cells infected with coronavirus. GS-441524 could strongly inhibits feline infectious peritonitis virus (FIPV), with an EC50 of 0.78 μM[1][2][3].
Product Specifications
CAS Number
1191237-69-0
UNSPSC
12352005
Hazard Statement
H315, H317, H318, H334, H335, H341, H361, H371
Target
DNA/RNA Synthesis; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/GS-441524.html
Purity
99.94
Solubility
DMSO : 83.33 mg/mL (ultrasonic)
Smiles
N#C[C@@]1(C2=CC=C3N2N=CN=C3N)O[C@H](CO)[C@@H](O)[C@H]1O
Molecular Formula
C12H13N5O4
Molecular Weight
291.26
Precautions
H315, H317, H318, H334, H335, H341, H361, H371
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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