Leukotriene B4 ethanolamide

Leukotriene B4 ethanolamide (LTB4 ethanolamide) is an antagonist and a partial agonist for Leukotriene B4 (LTB4) receptor 1 (BLTR1) . Leukotriene B4 ethanolamide ameliorates the tumor progression, which is only asscociated with inflammation[1][2].

Product Specifications

CAS Number

[877459-63-7]

Product Name Alternative

LTB4 ethanolamide

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

Endogenous Metabolite; Leukotriene Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/leukotriene-b4-ethanolamide.html

Solubility

10 mM in DMSO

Smiles

CCCCC/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(NCCO)=O

Molecular Formula

C22H37NO4

Molecular Weight

379.53

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]McHugh D, et al., Novel compounds that interact with both leukotriene B4 receptors and vanilloid TRPV1 receptors. J Pharmacol Exp Ther. 2006 Feb;316 (2) :955-65.|[2]Bachi AL, et al., Leukotriene B4 creates a favorable microenvironment for murine melanoma growth. Mol Cancer Res. 2009 Sep;7 (9) :1417-24.