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XRK3F2

XRK3F2 is an inhibitor of p62 (Sequestosome-1) -ZZ/ domain.

Product Specifications

CAS Number

2375193-43-2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Autophagy; p62

Type

Reference compound

Related Pathways

Autophagy

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/XRK3F2.html

Purity

99.08

Solubility

DMSO : 150 mg/mL (ultrasonic) |H2O : 0.91 mg/mL (ultrasonic)

Smiles

FC(C=C1)=CC=C1COC2=C(OCC3=CC=C(F)C=C3)C=C(CNCCO)C=C2.Cl

Molecular Formula

C23H24ClF2NO3

Molecular Weight

435.89

Precautions

H302, H315, H319, H335

References & Citations

[1]Adamik J, et al. XRK3F2 Inhibition of p62-ZZ Domain Signaling Rescues Myeloma-Induced GFI1-Driven Epigenetic Repression of the Runx2 Gene in Pre-osteoblasts to Overcome Differentiation Suppression. Front Endocrinol (Lausanne) . 2018 Jun 29;9:344.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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