XRK3F2
XRK3F2 is an inhibitor of p62 (Sequestosome-1) -ZZ/ domain.
Product Specifications
CAS Number
[2375193-43-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; p62
Type
Reference compound
Related Pathways
Autophagy
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/XRK3F2.html
Purity
99.08
Solubility
DMSO : 150 mg/mL (ultrasonic) |H2O : 0.91 mg/mL (ultrasonic)
Smiles
FC(C=C1)=CC=C1COC2=C(OCC3=CC=C(F)C=C3)C=C(CNCCO)C=C2.Cl
Molecular Formula
C23H24ClF2NO3
Molecular Weight
435.89
Precautions
H302, H315, H319, H335
References & Citations
[1]Adamik J, et al. XRK3F2 Inhibition of p62-ZZ Domain Signaling Rescues Myeloma-Induced GFI1-Driven Epigenetic Repression of the Runx2 Gene in Pre-osteoblasts to Overcome Differentiation Suppression. Front Endocrinol (Lausanne) . 2018 Jun 29;9:344.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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