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VISTA/B7-H5, Cynomolgus (HEK293, Fc)

Selected Variant

HY-P73482

Size: 1 Each

VISTA/B7-H5 Protein is a B7 family member that maintains T cell and myeloid quiescence and is a promising target for combination cancer immunotherapy. VISTA not only acts as a ligand expressed on antigenpresenting cells, but also functions as a receptor on T cells. VISTA inhibits T cell activation, proliferation, and cytokine production. VISTA/B7-H5 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-hFc labeled tag.

Product Specifications

Product Name Alternative

VISTA/B7-H5 Protein, Cynomolgus (HEK293, Fc), Cynomolgus, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/vista-b7-h5-protein-cynomolgus-hek293-fc.html

Molecular Formula

102116468 (Gene_ID) A0A2K5UV12 (F33-A194) (Accession)

Molecular Weight

Approximately 44.9 kDa

References & Citations

[1]Yuan L, et al. VISTA: A Mediator of Quiescence and a Promising Target in Cancer Immunotherapy. Trends Immunol. 2021 Mar;42 (3) :209-227.|[2]Huang X, et al. VISTA: an immune regulatory protein checking tumor and immune cells in cancer immunotherapy. J Hematol Oncol. 2020 Jun 29;13 (1) :83.|[3]Nowak EC, et al. Immunoregulatory functions of VISTA. Immunol Rev. 2017 Mar;276 (1) :66-79.

Shipping Conditions

Dry ice.

Scientific Category

Recombinant Proteins

Price

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