GSK931145
GSK931145 is a glycine transporter 1 (GlyT1) inhibitor with anti-epileptic activity. GSK931145 exhibits a low minimum effective dose in the maximum electrical stimulation threshold test, indicating that it has a significant anti-epileptic effect. GSK931145 is also suitable as a positron emission tomography (PET) radioligand for quantifying the availability of glycine transporters in the living brain[1].
Product Specifications
CAS Number
896117-64-9
UNSPSC
12352005
Target
GlyT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gsk931145.html
Smiles
O=C(C1=C(C)C=CC=C1C)NC(C2(CCCC2)N(C)C)C3=CC=CC=C3
Molecular Formula
C23H30N2O
Molecular Weight
350.50
References & Citations
[1]Glycine transporter 1 (GlyT1) inhibitors exhibit anticonvulsant properties in the rat maximal electroshock threshold (MEST) test
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
ECD CRISPR All-in-one AAV vector set (with saCas9)(Human)
African Swine Fever Virus Antigen One-Step
PE-Linked Polyclonal Antibody to Leucine Twenty Homeobox (LEUTX)
PE-Linked Polyclonal Antibody to Leucine Twenty Homeobox (LEUTX)