β-Amyloid (1-40), FAM-labeled (TFA)

β-Amyloid (1-40), FAM-labeled TFA is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λex= 492 nm and λem= 518 nm) .

Product Specifications

UNSPSC

12352209

Target

Amyloid-β

Type

Peptides

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/β-amyloid-1-40-fam-labeled-tfa.html

Purity

99.71

Solubility

DMSO : 10 mg/mL (ultrasonic)

Smiles

O=C([C@@H](NC(C1=CC=C2C(C(OC23C4=CC=C(O)C=C4OC5=CC(O)=CC=C53)=O)=C1)=O)CC(O)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(O)=O)C(C)C)=O)C(C)C)=O)=O)=O)C(C)C)=O)CCSC)=O)CC(C)C)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)C)=O)=O)CCCCN)=O)CC(N)=O)=O)CO)=O)=O)C(C)C)=O)CC(O)=O)=O)CCC(O)=O)=O)C)=O)CC6=CC=CC=C6)=O)CC7=CC=CC=C7)=O)C(C)C)=O)CC(C)C)=O)CCCCN)=O)CCC(N)=O)=O)CC8=CNC=N8)=O)CC9=CNC=N9)=O)C(C)C)=O)CCC(O)=O)=O)CC%10=CC=C(O)C=C%10)=O)=O)CO)=O)CC(O)=O)=O)CC%11=CNC=N%11)=O)CCCNC(N)=N)=O)CC%12=CC=CC=C%12)=O)CCC(O)=O)=O)C.O=C(O)C(F)(F)F

Molecular Formula

C217H306N53F3O66S

Molecular Weight

4802.22

References & Citations

[1]L M Jungbauer, et al. Preparation of fluorescently-labeled amyloid-beta peptide assemblies: the effect of fluorophore conjugation on structure and function. J Mol Recognit. Sep-Oct 2009;22 (5) :403-13.|[2]Sonia Mazzitelli, et al. Amyloid-β 1-24 C-terminal truncated fragment promotes amyloid-β 1-42 aggregate formation in the healthy brain. Acta Neuropathol Commun. 2016 Oct 10;4 (1) :110.