Tumor targeted pro-apoptotic peptide
Tumor targeted pro-apoptotic peptide (CNGRC-GG-D (KLAKLAK) 2) is an anti-tumor peptide. Tumor targeted pro-apoptotic peptide disrupts mitochondrial membranes and promotes apoptosis, showing anticancer activity in mice[1].
Product Specifications
CAS Number
[1926163-30-5]
UNSPSC
12352209
Target
Apoptosis
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tumor-targeted-pro-apoptotic-peptide.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1NC([C@@H](NC(CNC([C@@H](NC([C@H](CSSC1)N)=O)CC(N)=O)=O)=O)CCCNC(N)=N)=O)NCC(NCC(N[C@H](CCCCN)C(N[C@H](CC(C)C)C(N[C@H](C)C(N[C@H](CCCCN)C(N[C@H](CC(C)C)C(N[C@H](C)C(N[C@H](CCCCN)C(N[C@H](CCCCN)C(N[C@H](CC(C)C)C(N[C@H](C)C(N[C@H](CCCCN)C(N[C@H](CC(C)C)C(N[C@H](C)C(N[C@@H](C(N)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C94H174N32O22S2
Molecular Weight
2168.72
References & Citations
[1]Ellerby HM, et al. Anti-cancer activity of targeted pro-apoptotic peptides. Nat Med. 1999 Sep;5 (9) :1032-8.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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