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Tumor targeted pro-apoptotic peptide

Tumor targeted pro-apoptotic peptide (CNGRC-GG-D (KLAKLAK) 2) is an anti-tumor peptide. Tumor targeted pro-apoptotic peptide disrupts mitochondrial membranes and promotes apoptosis, showing anticancer activity in mice[1].

Product Specifications

CAS Number

[1926163-30-5]

UNSPSC

12352209

Target

Apoptosis

Type

Peptides

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tumor-targeted-pro-apoptotic-peptide.html

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1NC([C@@H](NC(CNC([C@@H](NC([C@H](CSSC1)N)=O)CC(N)=O)=O)=O)CCCNC(N)=N)=O)NCC(NCC(N[C@H](CCCCN)C(N[C@H](CC(C)C)C(N[C@H](C)C(N[C@H](CCCCN)C(N[C@H](CC(C)C)C(N[C@H](C)C(N[C@H](CCCCN)C(N[C@H](CCCCN)C(N[C@H](CC(C)C)C(N[C@H](C)C(N[C@H](CCCCN)C(N[C@H](CC(C)C)C(N[C@H](C)C(N[C@@H](C(N)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C94H174N32O22S2

Molecular Weight

2168.72

References & Citations

[1]Ellerby HM, et al. Anti-cancer activity of targeted pro-apoptotic peptides. Nat Med. 1999 Sep;5 (9) :1032-8.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

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