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Tavilermide

Tavilermide is a selective, partial agonist of TrkA, or a nerve growth factor (NGF) mimetic.

Product Specifications

CAS Number

263251-78-1

Product Name Alternative

MIM-D3

UNSPSC

12352005

Target

Trk Receptor

Type

Reference compound

Related Pathways

Neuronal Signaling; Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Tavilermide.html

Purity

99.57

Solubility

H2O : 2 mg/mL (ultrasonic) |NH4OH : 50 mg/mL (ultrasonic; adjust pH to 10 with NH4OH)

Smiles

O=C(O)CC[C@H](N1)C(N[C@@H](CCCCN)C(N[C@H](C(NCC(O)=O)=O)CCOC2=CC=C([N+]([O-])=O)C=C2C1=O)=O)=O

Molecular Formula

C24H32N6O11

Molecular Weight

580.54

References & Citations

[1]Meerovitch K, et al. Safety and efficacy of MIM-D3 ophthalmic solutions in a randomized, placebo-controlled Phase 2 clinical trial in patients with dry eye. Clin Ophthalmol. 2013;7:1275-85.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Isoform

TrkA

Available Sizes

Frequently Asked Questions

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