Tavilermide
Tavilermide is a selective, partial agonist of TrkA, or a nerve growth factor (NGF) mimetic.
Product Specifications
CAS Number
[263251-78-1]
Product Name Alternative
MIM-D3
UNSPSC
12352005
Target
Trk Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Tavilermide.html
Purity
99.57
Solubility
H2O : 2 mg/mL (ultrasonic) |NH4OH : 50 mg/mL (ultrasonic; adjust pH to 10 with NH4OH)
Smiles
O=C(O)CC[C@H](N1)C(N[C@@H](CCCCN)C(N[C@H](C(NCC(O)=O)=O)CCOC2=CC=C([N+]([O-])=O)C=C2C1=O)=O)=O
Molecular Formula
C24H32N6O11
Molecular Weight
580.54
References & Citations
[1]Meerovitch K, et al. Safety and efficacy of MIM-D3 ophthalmic solutions in a randomized, placebo-controlled Phase 2 clinical trial in patients with dry eye. Clin Ophthalmol. 2013;7:1275-85.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
TrkA
Available Sizes
Curated Selection
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