4-Hydroxyphenylacetic acid
4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2[1].
Product Specifications
CAS Number
156-38-7
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Endogenous Metabolite; Keap1-Nrf2
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/4-Hydroxyphenylacetic_acid.html
Purity
99.96
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(O)CC1=CC=C(O)C=C1
Molecular Formula
C8H8O3
Molecular Weight
152.15
Precautions
H315, H319, H335
References & Citations
[1]Zhao H, et al. 4-Hydroxyphenylacetic Acid Prevents Acute APAP-Induced Liver Injury by Increasing Phase IIand Antioxidant Enzymes in Mice. Front Pharmacol. 2018 Jun 19;9:653.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite; Microbial Metabolite
Available Sizes
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