4-Hydroxyphenylacetic acid

4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2[1].

Product Specifications

CAS Number

[156-38-7]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite; Keap1-Nrf2

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/4-Hydroxyphenylacetic_acid.html

Purity

99.96

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(O)CC1=CC=C(O)C=C1

Molecular Formula

C8H8O3

Molecular Weight

152.15

Precautions

H315, H319, H335

References & Citations

[1]Zhao H, et al. 4-Hydroxyphenylacetic Acid Prevents Acute APAP-Induced Liver Injury by Increasing Phase IIand Antioxidant Enzymes in Mice. Front Pharmacol. 2018 Jun 19;9:653.