(3R,4S)-Tofacitinib
Product Specifications
UNSPSC Description
(3R,4S)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.
Target Antigen
JAK
Type
Reference compound
Related Pathways
Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/_3R,4S_-Tofacitinib.html
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN(C1=NC=NC2=C1C=CN2)[C@@H]3[C@@H](C)CCN(C(CC#N)=O)C3
Molecular Weight
312.37
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-40354D/3R-4S-Tofacitinib-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-40354D/3R-4S-Tofacitinib-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
1092578-46-5
Available Sizes
Curated Selection
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