Bikinin
Bikinin is a non-steroidal, ATP-competitive inhibitor of plant GSK-3/Shaggy-like kinases and activates BR (brassinosteroids) signaling.
Product Specifications
CAS Number
[188011-69-0]
Product Name Alternative
Abrasin
UNSPSC
12352005
Hazard Statement
H302, H319
Target
GSK-3
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR; Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Bikinin.html
Purity
99.95
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(O)CCC(NC1=NC=C(Br)C=C1)=O
Molecular Formula
C9H9BrN2O3
Molecular Weight
273.08
Precautions
H302, H319
References & Citations
[1]Deng XG, et al. Role of brassinosteroid signaling in modulating Tobacco mosaic virus resistance in Nicotiana benthamiana. Sci Rep. 2016 Feb 3;6:20579.|[2]Rozhon W, et al. Bikinin-like inhibitors targeting GSK3/Shaggy-like kinases: characterisation of novel compounds and elucidation of their catabolism in planta. BMC Plant Biol. 2014 Jun 19;14:172.|[3]De Rybel B, et al. Chemical inhibition of a subset of Arabidopsis thaliana GSK3-like kinases activates brassinosteroid signaling. Chem Biol. 2009 Jun 26;16 (6) :594-604.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GSK-3
Available Sizes
Curated Selection
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