8-Br-cGMP-AM
8-Br-cGMP-AM is a derivative of 8-Br-cGMP. As an activator of PKG (cGMP-dependent protein kinase), it can lead to a variety of biological effects such as vasodilation and platelet inhibition. 8-Br-cGMP-AM can be used in the study of cardiovascular diseases[1].
Product Specifications
CAS Number
[272445-71-3]
UNSPSC
12352005
Target
PKG
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/8-br-cgmp-am.html
Smiles
O[C@@H]1[C@H](OP2(OCOC(C)=O)=O)[C@@H](CO2)O[C@H]1N3C(Br)=NC4=C3N=C(N)NC4=O
Molecular Formula
C13H15BrN5O9P
Molecular Weight
496.16
References & Citations
[1]Butt E. cGMP-dependent protein kinase modulators[J]. cGMP: Generators, Effectors and Therapeutic Implications, 2009: 409-421.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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