8-Br-cGMP-AM

8-Br-cGMP-AM is a derivative of 8-Br-cGMP. As an activator of PKG (cGMP-dependent protein kinase), it can lead to a variety of biological effects such as vasodilation and platelet inhibition. 8-Br-cGMP-AM can be used in the study of cardiovascular diseases[1].

Product Specifications

CAS Number

[272445-71-3]

UNSPSC

12352005

Target

PKG

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/8-br-cgmp-am.html

Smiles

O[C@@H]1[C@H](OP2(OCOC(C)=O)=O)[C@@H](CO2)O[C@H]1N3C(Br)=NC4=C3N=C(N)NC4=O

Molecular Formula

C13H15BrN5O9P

Molecular Weight

496.16

References & Citations

[1]Butt E. cGMP-dependent protein kinase modulators[J]. cGMP: Generators, Effectors and Therapeutic Implications, 2009: 409-421.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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