ICRT3
ICRT3 is an inhibitor of both Wnt and β-catenin-responsive transcription.
Product Specifications
CAS Number
901751-47-1
UNSPSC
12352005
Hazard Statement
H302, H315, H318, H335, H413
Target
Apoptosis; Wnt
Type
Reference compound
Related Pathways
Apoptosis; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/iCRT3.html
Purity
99.55
Solubility
DMSO : 150 mg/mL (ultrasonic; warming)
Smiles
O=C(NCCC1=CC=CC=C1)CSCC2=C(C)OC(C3=CC=C(CC)C=C3)=N2
Molecular Formula
C23H26N2O2S
Molecular Weight
394.53
Precautions
H302, H315, H318, H335, H413
References & Citations
[1]Xiao H, et al. A Novel Positive Feedback Loop Between NTSR1 and Wnt/β-Catenin Contributes to Tumor Growth of Glioblastoma. Cell Physiol Biochem. 2017 Oct 24;43 (5) :2133-2142.|[2]Chatterjee SS, et al. Inhibition of β-catenin-TCF1 interaction delays differentiation of mouse embryonic stem cells. J Cell Biol. 2015 Oct 12;211 (1) :39-51.|[3]Sharma A, et al. Mitigation of sepsis-induced inflammatory responses and organ injury through targeting Wnt/β-catenin signaling. doi: 10.1038/s41598-017-08711-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GAF-2305-40 1 mL
Colloidal Gold Conjugated Goat Affinity Purified Antibody to Monkey IgG, 40nm
Sign In for Pricing
View Details 
BNC042039-500 1x 500 µL
Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
P014-568-500 1x 500 µL
CD81 Recombinant Monoclonal Mouse Antibody (2304.81), CF®568 Conjugate - Biotium Choice
Sign In for Pricing
View Details 