Human IL-23 alpha & Mouse IL-12 beta Heterodimer (HEK293, His)

IL-23 and IL12B together constitute the pro-inflammatory cytokine IL-23, which is crucial in innate and adaptive immunity. IL-23 is released by antigen-presenting cells such as dendritic cells or macrophages, binds to IL12RB1 and IL23R, and activates JAK2 and TYK2. Human IL-23 alpha & Mouse IL-12 beta Heterodimer Protein (HEK293, His) is a recombinant protein dimer complex containing mouse, human-derived Human IL-23 alpha & Mouse IL-12 beta Heterodimer protein, expressed by HEK293 , with C-6*His labeled tag.

RAVPGGSSPA WTQCQQLSQK LCTLAWSAHP LVGHMDLREE GDEETTNDVP HIQCGDGCDP QGLRDNSQFC LQRIHQGLIF YEKLLGSDIF TGEPSLLPDS PVGQLHASLL GLSQLLQPEG HHWETQQIPS LSPSQPWQRL LLRFKILRSL QAFVAVAARV FAHGAATLSP &MWELEKDVY VVEVDWTPDA PGETVNLTCD TPEEDDITWT SDQRHGVIGS GKTLTITVKE FLDAGQYTCH KGGETLSHSH LLLHKKENGI WSTEILKNFK NKTFLKCEAP NYSGRFTCSW LVQRNMDLKF NIKSSSSSPD SRAVTCGMAS LSAEKVTLDQ RDYEKYSVSC QEDVTCPTAE ETLPIELALE ARQQNKYENY STSFFIRDII KPDPPKNLQM KPLKNSQVEV SWEYPDSWST PHSYFSLKFF VRIQRKKEKM KETEEGCNQK GAFLVEKTST EVQCKGGNVC VQAQDRYYNS SCSKWACVPC RVRS