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KRAS G12D inhibitor 20

KRAS G12D inhibitor 20 (Compound 14) is a selective G12D KRAS inhibitor. KRAS G12D inhibitor 20 has antitumor activity[1].

Product Specifications

UNSPSC

12352005

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kras-g12d-inhibitor-20.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCCC1N(C=CC=C2)C2N=N1)C3=NNC4CCCCCC43

Molecular Formula

C18H26N6O

Molecular Weight

342.44

References & Citations

[1]Ranđelović I, , et al. Gluing GAP to RAS Mutants: A New Approach to an Old Problem in Cancer Drug Development. Int J Mol Sci. 2024 Feb 22;25 (5) :2572.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

K-Ras

Frequently Asked Questions

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