KRAS G12D inhibitor 20
Product Specifications
UNSPSC Description
KRAS G12D inhibitor 20 (Compound 14) is a selective G12D KRAS inhibitor. KRAS G12D inhibitor 20 has antitumor activity[1].
Target Antigen
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein;MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12d-inhibitor-20.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCCC1N(C=CC=C2)C2N=N1)C3=NNC4CCCCCC43
Molecular Weight
342.44
References & Citations
[1]Ranđelović I, ,et al. Gluing GAP to RAS Mutants: A New Approach to an Old Problem in Cancer Drug Development. Int J Mol Sci. 2024 Feb 22;25(5):2572.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162366/KRAS-G12D-inhibitor-20-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162366/
Clinical Information
No Development Reported
Curated Selection
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