Pramiracetam
Pramiracetam (CI-879 free base) is a PREP (prolyl endopeptidase) inhibitor. Pramiracetam improves cognitive impairment caused by traumatic brain injury. Pramiracetam can be used in the study of neurodegenerative diseases[1][2].
Product Specifications
CAS Number
[68497-62-1]
Product Name Alternative
CI-879 (free base)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Prolyl Endopeptidase (PREP)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pramiracetam.html
Purity
98.0
Solubility
DMSO : ≥ 100 mg/mL|H2O : ≥ 100 mg/mL
Smiles
O=C(NCCN(C(C)C)C(C)C)CN1C(CCC1)=O
Molecular Formula
C14H27N3O2
Molecular Weight
269.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Murray CL, et al. The effect of pramiracetam (CI-879) on the acquisition of a radial arm maze task. Psychopharmacology (Berl) . 1986;89 (3) :378-81.|[2]Yoshimoto T, et al. Specific inhibitors for prolyl endopeptidase and their anti-amnesic effect. J Pharmacobiodyn. 1987 Dec;10 (12) :730-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
C2398-01Q-ML405 100 µL
CD44 (CD 44, CDw44, ECM III, ECMRIII, Epican, Extracellular Matrix Receptor III, GP90 Lymphocyte Homing Adhesion Receptor, HCAM, HCELL, Heparan Sulfate Proteoglycan, Hermes Antigen, HUTCH1, Hyaluronate Receptor, Indian Blood Group, Inlu Related p80 Glycoprotein, lhr, Ly 24, MC56, MDU2, MDU3, MGC10468, MIC4, MUTCH1, PGP1, Phagocytic Glycoprotein 1, Phagocytic Glycoprotein I) (MaxLight 405) discontinued
Ask
View Details MBS1102265-01 0.02 mg (E-Coli)
Recombinant Francisella tularensis subsp. tularensis Protein hfq (hfq)
Ask
View Details 
MBS1102265-02 0.1 mg (E-Coli)
Recombinant Francisella tularensis subsp. tularensis Protein hfq (hfq)
Ask
View Details MBS1102265-03 0.02 mg (Yeast)
Recombinant Francisella tularensis subsp. tularensis Protein hfq (hfq)
Ask
View Details 
MBS1102265-04 0.1 mg (Yeast)
Recombinant Francisella tularensis subsp. tularensis Protein hfq (hfq)
Ask
View Details