Pramiracetam
Pramiracetam (CI-879 free base) is a PREP (prolyl endopeptidase) inhibitor. Pramiracetam improves cognitive impairment caused by traumatic brain injury. Pramiracetam can be used in the study of neurodegenerative diseases[1][2].
Product Specifications
CAS Number
68497-62-1
Product Name Alternative
CI-879 (free base)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Prolyl Endopeptidase (PREP)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pramiracetam.html
Purity
98.0
Solubility
DMSO : ≥ 100 mg/mL|H2O : ≥ 100 mg/mL
Smiles
O=C(NCCN(C(C)C)C(C)C)CN1C(CCC1)=O
Molecular Formula
C14H27N3O2
Molecular Weight
269.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Murray CL, et al. The effect of pramiracetam (CI-879) on the acquisition of a radial arm maze task. Psychopharmacology (Berl) . 1986;89 (3) :378-81.|[2]Yoshimoto T, et al. Specific inhibitors for prolyl endopeptidase and their anti-amnesic effect. J Pharmacobiodyn. 1987 Dec;10 (12) :730-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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