Pramiracetam

Pramiracetam (CI-879 free base) is a PREP (prolyl endopeptidase) inhibitor. Pramiracetam improves cognitive impairment caused by traumatic brain injury. Pramiracetam can be used in the study of neurodegenerative diseases[1][2].

Product Specifications

CAS Number

[68497-62-1]

Product Name Alternative

CI-879 (free base)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Prolyl Endopeptidase (PREP)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/pramiracetam.html

Purity

98.0

Solubility

DMSO : ≥ 100 mg/mL|H2O : ≥ 100 mg/mL

Smiles

O=C(NCCN(C(C)C)C(C)C)CN1C(CCC1)=O

Molecular Formula

C14H27N3O2

Molecular Weight

269.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Murray CL, et al. The effect of pramiracetam (CI-879) on the acquisition of a radial arm maze task. Psychopharmacology (Berl) . 1986;89 (3) :378-81.|[2]Yoshimoto T, et al. Specific inhibitors for prolyl endopeptidase and their anti-amnesic effect. J Pharmacobiodyn. 1987 Dec;10 (12) :730-5.