DCLX069
DCLX069 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 value of 17.9 µM. DCLX069 shows less active against PRMT4 and PRMT6. DCLX069 has anticancer effects[1].
Product Specifications
CAS Number
[792946-69-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dclx069.html
Concentration
10mM
Purity
98.03
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C(N)=C1)N2CCN(CC2)CC3=CC=CC=C3)OCC
Molecular Formula
C20H25N3O2
Molecular Weight
339.43
Precautions
H302, H315, H319
References & Citations
[1]Yiqian Xie, et al. Virtual screening and biological evaluation of novel small molecular inhibitors against protein arginine methyltransferase 1 (PRMT1) . Org Biomol Chem. 2014 Dec 21;12 (47) :9665-73.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PRMT1
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
251796-FITC 100 µL
SMAD3 (SMAD Family Member 3, DKFZp586N0721, DKFZp686J10186, HSPC193, HsT17436, JV15-2, MADH3, MGC60396) (FITC)
Ask
View Details