DCLX069

DCLX069 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 value of 17.9 µM. DCLX069 shows less active against PRMT4 and PRMT6. DCLX069 has anticancer effects[1].

Product Specifications

CAS Number

[792946-69-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Histone Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dclx069.html

Concentration

10mM

Purity

98.03

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C(N)=C1)N2CCN(CC2)CC3=CC=CC=C3)OCC

Molecular Formula

C20H25N3O2

Molecular Weight

339.43

Precautions

H302, H315, H319

References & Citations

[1]Yiqian Xie, et al. Virtual screening and biological evaluation of novel small molecular inhibitors against protein arginine methyltransferase 1 (PRMT1) . Org Biomol Chem. 2014 Dec 21;12 (47) :9665-73.