Scopine
Scopine is a metabolite of Scopolamine and brain-targeting compound. Scopine significantly increases the brain exposure of Chlorambucil (HY-13593) and enhances its anti-glioma activity. Scopine can be used in targeted therapy research for brain gliomas[1].
Product Specifications
CAS Number
498-45-3
Product Name Alternative
6,7-Epoxytropine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/scopine.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
[H][C@@]12[C@]3([H])[C@@]([H])(O3)[C@@](C[C@H](O)C2)([H])N1C
Molecular Formula
C8H13NO2
Molecular Weight
155.19
Precautions
H302, H315, H319, H335
References & Citations
[1]Wang X, et al. Scopine as a novel brain-targeting moiety enhances the brain uptake of chlorambucil. Bioconjug Chem. 2014 Nov 19;25 (11) :2046-54.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
α adrenergic receptor
Citation 01
Molecules. 2025 Oct 23;30 (21) :4170.|Anal Bioanal Chem. 2025 Jun;417 (14) :3169-3176.
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