7-Azido-4-methylcoumarin

7-Azido-4-methylcoumarin is a fluorescent hydrogen sulfide (H2S) probe. 7-Azido-4-methylcoumarin serves as a highly sensitive assay for cystathionine β-synthase activity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[95633-27-5]

Product Name Alternative

Erythromycin Cyclocarbonate

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Fluorescent Dye

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/7-azido-4-methylcoumarin.html

Purity

98.90

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

[N-]=[N+]=NC1=CC(OC(C=C2C)=O)=C2C=C1

Molecular Formula

C10H7N3O2

Molecular Weight

201.18

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Megan K Thorson, et al. Identification of cystathionine β-synthase inhibitors using a hydrogen sulfide selective probe. Angew Chem Int Ed Engl. 2013 Apr 22;52 (17) :4641-4.