2- (2- ((6-Chlorohexyl) oxy) ethoxy) acetic acid
2- (2- ((6-Chlorohexyl) oxy) ethoxy) acetic acid is a PROTACT linker in PROTAC SMARCA2/4-degrader-34 (HY-169279) [1].
Product Specifications
CAS Number
[2231744-57-1]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-2-6-chlorohexyl-oxy-ethoxy-acetic-acid.html
Purity
95.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClCCCCCCOCCOCC(O)=O
Molecular Formula
C10H19ClO4
Molecular Weight
238.71
Precautions
H302, H315, H319, H335
References & Citations
[1]Andrew D Huber, et al. First-in-Class Small Molecule Degrader of Pregnane X Receptor Enhances Chemotherapy Efficacy. J Med Chem. 2024 Oct 24;67 (20) :18549-18575.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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