DS44470011
DS44470011 is a hypoxia-inducing factor prolyl hydroxylase (HIF-PHD) inhibitor. DS44470011 has oral activity. DS44470011 promotes cell release of erythropoietin (EPO) . DS44470011 can be used in the research of renal anemia[1].
Product Specifications
CAS Number
1192586-35-8
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ds44470011.html
Smiles
OC1=C(C(NCC(O)=O)=O)N=C(CC2=CC=C(C3=CC=CC=C3)C=C2)N=C1C
Molecular Formula
C21H19N3O4
Molecular Weight
377.39
References & Citations
[1]ukuda T, et al. Discovery of DS44470011: An oral hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of renal anemia. Bioorg Med Chem Lett. 2024 Aug 1;108:129799.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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