R110
R110 is a potent, competitive inhibitor of macrophage migration inhibitory factor 2 (MIF2) tautomerase with an IC50 of 15 μM. R110 has the potential for the research of cancer diseases[1].
Product Specifications
CAS Number
[1985622-33-0]
Product Name Alternative
N-Lauroyl-D-erythro-sphingosine; N-Laurylsphingosine
UNSPSC
12352005
Target
Macrophage migration inhibitory factor (MIF)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r110.html
Purity
99.90
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=C(N)SC(C2=CC=C(Cl)C=C2)=C1)NCCCC
Molecular Formula
C15H17ClN2OS
Molecular Weight
308.83
References & Citations
[1]Xiao Z, et al. Thieno[2,3-d]pyrimidine-2,4 (1H,3H) -dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells. J Med Chem. 2022 Feb 10;65 (3) :2059-2077.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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