Loperamide (hydrochloride)
Loperamide (hydrochloride) (R-18553 (hydrochloride) ) is an opioid receptor agonist[1][2][3]. Loperamide hydrochloride is a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. Loperamide hydrochloride has anti-diarrheal effect[4].
Product Specifications
CAS Number
34552-83-5
Product Name Alternative
R-18553 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H301
Target
Autophagy; Opioid Receptor
Type
Reference compound
Related Pathways
Autophagy; GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Loperamide-hydrochloride.html
Concentration
10mM
Purity
99.89
Solubility
DMSO : 43.75 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 1 mg/mL (ultrasonic)
Smiles
O=C(N(C)C)C(C1=CC=CC=C1)(C2=CC=CC=C2)CCN3CCC(O)(C4=CC=C(Cl)C=C4)CC3.Cl
Molecular Formula
C29H34Cl2N2O2
Molecular Weight
513.50
Precautions
H301
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Available Sizes
Frequently Asked Questions
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