CARM1-IN-1 (hydrochloride)
Product Specifications
UNSPSC Description
CARM1-IN-1 hydrochloride is a potent and specific CARM1 (Coactivator-associated arginine methyltransferase 1) inhibitor with IC50 of 8.6 uM; shows very low activity against PRMT1 and SET7.
Target Antigen
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/CARM1-IN-1-hydrochloride.html
Purity
95.13
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
[H]Cl.O=C1/C(CN(CC2=CC=CC=C2)C/C1=C\C3=CC=C(O)C(Br)=C3)=C/C4=CC=C(O)C(Br)=C4
Molecular Weight
591.72
References & Citations
[1]Cheng D, et al. Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity. J Med Chem. 2011 Jul 14;54(13):4928-32.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12759A/CARM1-IN-1-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12759A/CARM1-IN-1-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2070018-31-2
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal SETD7/9 Antibody (7C1B7E1) [Janelia Fluor 549]](https://cdn.genprice.uk/genprice/genprice5.png)
NBP3-06625JF549 0.1 mL
Mouse Monoclonal SETD7/9 Antibody (7C1B7E1) [Janelia Fluor 549]
Ask
View Details 
MBS1499066-01 0.05 mg
Rabbit anti-human CUE domain-containing protein 2 polyclonal Antibody
Ask
View Details MBS1499066-02 0.1 mg
Rabbit anti-human CUE domain-containing protein 2 polyclonal Antibody
Ask
View Details MBS1499066-03 5x 0.1 mg
Rabbit anti-human CUE domain-containing protein 2 polyclonal Antibody
Ask
View Details