IPI-3063
IPI-3063 is a potent and selective PI3K p110δ inhibitor with an IC50 of 2.5 ± 1.2 nM.
Product Specifications
CAS Number
[1425043-73-7]
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/IPI-3063.html
Concentration
10mM
Purity
99.59
Solubility
DMSO : ≥ 62.5 mg/mL
Smiles
N#CC1=C(N[C@H](C2=CC3=C(C(N2C(C)C)=O)C(C(C=C4)=CN(C)C4=O)=CC=C3)C)N=CN=C1N
Molecular Formula
C25H25N7O2
Molecular Weight
455.51
References & Citations
[1]Chiu H, et al. The Selective Phosphoinoside-3-Kinase p110δ Inhibitor IPI-3063 Potently Suppresses B Cell Survival, Proliferation, and Differentiation. Front Immunol. 2017 Jun 30;8:747.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ
Available Sizes
Curated Selection
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