Endotoxin inhibitor (TFA)

Endotoxin inhibitor TFA is a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor TFA inhibits the febrile response to LPS with very low toxicity and lethality[1].

Product Specifications

UNSPSC

12352209

Target

Interleukin Related

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/endotoxin-inhibitor-tfa.html

Purity

99.77

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)C(O)=O)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@@H](N)CCCCN)=O)=O)=O)=O)CCCCN)N[C@H]1CC2=CC=CC=C2.OC(C(F)(F)F)=O.[6]

Molecular Formula

C67H103F18N15O24S2

Molecular Weight

1908.72

References & Citations

[1]Toshihiko Katafuchi, et al. Endotoxin inhibitor blocks heat exposure-induced expression of brain cytokine mRNA in aged rats. Brain Res Mol Brain Res. 2003 Oct 21;118 (1-2) :24-32.