Bis-PEG6-acid
Bis-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[119189-70-7]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bis-peg6-acid.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
OC(CCOCCOCCOCCOCCOCCOCCC(O)=O)=O
Molecular Formula
C16H30O10
Molecular Weight
382.40
Precautions
H302, H315, H319, H335
References & Citations
[1]Zorba A, et al. Delineating the role of cooperativity in the design of potent PROTACs for BTK. Proc Natl Acad Sci U S A. 2018 Jul 31;115 (31) :E7285-E7292.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Curated Selection
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