Mibampator
Mibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors.
Product Specifications
CAS Number
375345-95-2
Product Name Alternative
LY451395
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/LY451395.html
Concentration
10mM
Purity
99.86
Solubility
DMSO : ≥ 25 mg/mL
Smiles
C[C@@H](CNS(C(C)C)(=O)=O)C1=CC=C(C2=CC=C(CCNS(C)(=O)=O)C=C2)C=C1
Molecular Formula
C21H30N2O4S2
Molecular Weight
438.60
Precautions
H302, H312, H332
References & Citations
[1]Zmijewski M, et al. Application of biocatalysis to drug metabolism: preparation of mammalian metabolites of a biaryl-bis-sulfonamide AMPA (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) receptor potentiator using Actinoplanes missouriensis. Drug Metab Dispos. 2006 Jun;34 (6) :925-31.|[2]Jones N, et al. AMPA receptor potentiation can prevent ethanol-induced intoxication. Neuropsychopharmacology. 2008 Jun;33 (7) :1713-23.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
AMPA Receptor
Available Sizes
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