Mibampator

Mibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors.

Product Specifications

CAS Number

[375345-95-2]

Product Name Alternative

LY451395

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/LY451395.html

Concentration

10mM

Purity

99.86

Solubility

DMSO : ≥ 25 mg/mL

Smiles

C[C@@H](CNS(C(C)C)(=O)=O)C1=CC=C(C2=CC=C(CCNS(C)(=O)=O)C=C2)C=C1

Molecular Formula

C21H30N2O4S2

Molecular Weight

438.60

Precautions

H302, H312, H332

References & Citations

[1]Zmijewski M, et al. Application of biocatalysis to drug metabolism: preparation of mammalian metabolites of a biaryl-bis-sulfonamide AMPA (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) receptor potentiator using Actinoplanes missouriensis. Drug Metab Dispos. 2006 Jun;34 (6) :925-31.|[2]Jones N, et al. AMPA receptor potentiation can prevent ethanol-induced intoxication. Neuropsychopharmacology. 2008 Jun;33 (7) :1713-23.