Cisatracurium (besylate)

Cisatracurium besylate (51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.

Product Specifications

CAS Number

[96946-42-8]

Product Name Alternative

51W89 (besylate) ; Cisatracurium (besilate)

UNSPSC

12352005

Hazard Statement

H301, H319

Target

Autophagy; nAChR

Type

Reference compound

Related Pathways

Autophagy; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Cisatracurium-besylate.html

Purity

98.0

Solubility

DMSO : 35 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL

Smiles

O=C(OCCCCCOC(CC[N@+]1(C)[C@H](CC2=CC=C(OC)C(OC)=C2)C3=C(C=C(OC)C(OC)=C3)CC1)=O)CC[N@+]4(C)[C@H](CC5=CC=C(OC)C(OC)=C5)C6=C(C=C(OC)C(OC)=C6)CC4.O=S(C7=CC=CC=C7)([O-])=O.O=S(C8=CC=CC=C8)([O-])=O

Molecular Formula

C65H82N2O18S2

Molecular Weight

1243.48

Precautions

H301, H319

References & Citations

[1]Dear, G.J., et al., Identification of urinary and biliary conjugated metabolites of the neuromuscular blocker 51W89 by liquid chromatography/mass spectrometry. Rapid Commun Mass Spectrom, 1995. 9 (14) : p. 1457-64.|[2]Serra, C.S. and A.C. Oliveira, Cisatracurium: myographical and electrophysiological studies in the isolated rat muscle. Fundam Clin Pharmacol, 2006. 20 (3) : p. 291-8.