Sodium new houttuyfonate
Sodium new houttuyfonate (SNH) is a partially reversible NDM-1 inhibitor with an IC50 of 14.2 μM. Sodium new houttuyfonate is an inhibitor against renin and angiotensin I converting enzyme (ACE) . Sodium new houttuyfonate can recover the antibacterial activity of Meropenem (HY-13678) against E. coli BL21/pET15b-blaNDM-1[1].
Product Specifications
CAS Number
[112714-99-5]
Product Name Alternative
SNH
UNSPSC
12352211
Target
Bacterial; Renin
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sodium-new-houttuyfonate.html
Purity
99.76
Solubility
DMSO : 8.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(C(O)CC(CCCCCCCCCCC)=O)(O[Na])=O
Molecular Formula
C14H27NaO5S
Molecular Weight
330.42
References & Citations
[1]Lifang Wang, et al. Novel partially reversible NDM-1 inhibitors based on the naturally occurring houttuynin. Bioorg Chem. 2024 Apr 3:147:107328.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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