Virginiamycin M1

Virginiamycin M1 (Pristinamycin IIA; Ostreogrycin A), produced by?Streptomyces virginiae, is an polyunsaturated macrocyclic lactone antibiotic and acts as a component of Virginiamycin (HY-112665) [1]. Virginiamycin M1 alone is against Staphylococcus aureus with a MIC of 0.25 μg/mL.

Product Specifications

CAS Number

[21411-53-0]

Product Name Alternative

Pristinamycin IIA; Ostreogrycin A

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Antibiotic; Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/virginiamycin-m1.html

Purity

99.13

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1N2C(C(O[C@@H]([C@@H](/C=C/C(NC/C=C\C(C)=C\[C@H](CC(CC3=NC1=CO3)=O)O)=O)C)C(C)C)=O)=CCC2

Molecular Formula

C28H35N3O7

Molecular Weight

525.59

Precautions

H315, H319, H335

References & Citations

[1]N Suzuki, et al. Purification and characterization of virginiamycin M1 reductase from Streptomyces virginiae. Antimicrob Agents Chemother. 1998 Nov;42 (11) :2985-8.|[2]Xiaoxin Xu, et al. Gold nanoparticle-based lateral flow strips for rapid and sensitive detection of Virginiamycin M1. Pages 764-777 | Received 18 Mar 2020, Accepted 27 Apr 2020