AZD-5069
AZD-5069 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment.
Product Specifications
CAS Number
[878385-84-3]
UNSPSC
12352005
Hazard Statement
H360
Target
CXCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Endocrinology
Assay Protocol
https://www.medchemexpress.com/AZD-5069.html
Purity
99.91
Solubility
DMSO : 90 mg/mL (ultrasonic)
Smiles
O=S(N1CCC1)(NC2=NC(SCC3=CC=CC(F)=C3F)=NC(O[C@H](C)[C@@H](O)CO)=C2)=O
Molecular Formula
C18H22F2N4O5S2
Molecular Weight
476.52
Precautions
H360
References & Citations
[1]Norman P, et al. Evidence on the identity of the CXCR2 antagonist AZD-5069. Expert Opin Ther Pat. 2013 Jan;23 (1) :113-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
CXCR2
Available Sizes
Curated Selection
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